Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions

Brief Summary

Normal cardiac and respiratory functions should be maintained during pediatric cardiac catheterization. Propofol has become a popular choice for sedation in children, however, it depresses cardiac and respiratory functions. Some investigators reported that ketamine attenuates its depressant effect, but it remains unclear whether ketamine reduces cardiac and respiratory depression caused by propofol in pediatric cardiac catheterization.

Intervention / Treatment

  • Drug: Control
  • Drug: Ket10
  • Drug: Ket20

Condition or Disease

  • Congenital Heart Disease
  • Sedated for Cardiac Catheterization

Phase

Study Design

Study type: Interventional
Status: Completed
Study results: No Results Available
Age: 6 Months to 10 Years   (Child)
Enrollment: 150 ()
Funded by: Other

Masking

Clinical Trial Dates

Start date: Jan 12, 2020
Primary Completion: May 13, 2020
Completion Date: May 13, 2020
Study First Posted: Dec 29, 2011
Results First Posted: Aug 31, 2020
Last Updated: Jul 30, 2013

Sponsors / Collaborators

Lead Sponsor: N/A
Responsible Party: N/A

Eligibility Criteria

Sex: All
Maximum Age: 10

More Details

NCT Number: NCT01501786
Other IDs: ketamine in sedation
Study URL: https://ClinicalTrials.gov/show/NCT01501786
Last updated: Jun 17, 2022