Use of Ketamine Associate With an Opioid for Sedation in ICU
Brief Summary
The aim of the study is to evaluate the impact of ketamine associated to an opioid for sedation of mechanically ventilated critically ill patients versus placebo. Sedation will be drive by nurses according to an algorithm. The investigators will evaluate the quantity of opioates used in each arm and the safety of ketamine.
Condition or Disease
- Sedation for Mechanical Ventilation
Phase
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 18 Years and older (Adult, Older Adult) |
| Enrollment: | 164 () |
| Funded by: | Other |
Masking |
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Clinical Trial Dates
| Start date: | Oct 11, 2020 | |
|---|---|---|
| Primary Completion: | Aug 12, 2020 | |
| Completion Date: | Aug 12, 2020 | |
| Study First Posted: | Mar 22, 2012 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Jan 14, 2013 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
All consecutive mechanically ventilated patients admitted in the intensive care unit (ICU)will be randomized to receive an infusion of 0.15 mg/kg/h of kétamine or placebo. Nurses and physicians will be blinded of the allocation arm. The infusion of ketamine will be stopped as soon as remifentanil will be discontinued by the physician.
Eligibility Criteria
| Sex: | All |
|---|---|
| Minimum Age: | 18 |
More Details
| NCT Number: | NCT01560390 |
|---|---|
| Acronym: | KetaRea |
| Other IDs: | CHU-0108 |
| Study URL: | https://ClinicalTrials.gov/show/NCT01560390 |
Last updated: Jun 17, 2022