Anesthesia for Retinopathy of Prematurity
Brief Summary
Premature infants experience more respiratory problems after surgical procedures. The investigators aimed to compare general anesthesia with sedation on the need for post-operative mechanical ventilation in infants undergoing retinopathy of prematurity surgery.
Condition or Disease
- Retinopathy
Phase
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 32 Weeks to 40 Weeks (Child) |
| Enrollment: | 60 () |
| Funded by: | Other |
Masking |
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Clinical Trial Dates
| Start date: | Sep 10, 2020 | |
|---|---|---|
| Primary Completion: | Dec 12, 2020 | |
| Completion Date: | Mar 13, 2020 | |
| Study First Posted: | Oct 07, 2013 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Oct 07, 2013 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
60 patients who underwent laser surgery due to retinopathy of prematurity (ROP) were included in the study. The sedation group (Group S, n=30), received 1 mg/kg ketamine and 1 mg/kg propofol as a bolus for induction. The patients then received an infusion of 100-150 mcg/kg/min propofol and 0.25mg/kg/h of ketamine for maintenance. In the general anesthesia group (Group G, n=30), anesthesia was induced using 8% sevoflurane by inhalation with 50% nitrous oxide in oxygen; endotracheal intubation was facilitated without use of a neuromuscular blocker agent. Anesthesia was maintained with sevoflurane (2%) and 50% nitrous oxide in oxygen. Our primary objective was to evaluate the need for post-operative mechanical ventilation.
Eligibility Criteria
| Sex: | All |
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More Details
| NCT Number: | NCT01955135 |
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| Other IDs: | 2010 /145 |
| Study URL: | https://ClinicalTrials.gov/show/NCT01955135 |
Last updated: Jan 27, 2021