Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation

Brief Summary

The aim of the study was to describe the relationship between the intensity of a standardized tetanic stimulation and the associated reflex pupillary dilation in patients under ketamine sedation.

After an intravenous bolus of 1 mg/kg of ketamine, tetanic stimulations were performed every minute at increasing intensities of 10, 20, 30, 40 and 60 milliamps (similar to the stimulations of neuromuscular blocking agents monitoring). Pupillary diameter was measured before and after each stimulation.

Intervention / Treatment

  • Drug: Ketamine
  • Procedure: Tetanic stimulations of incremental intensities

Condition or Disease

  • Pain
  • Anesthesia

Phase

Study Design

Study type: Interventional
Status: Completed
Study results: No Results Available
Age: 2 Years to 18 Years   (Child, Adult)
Enrollment: 24 ()
Funded by: Other

Masking

Clinical Trial Dates

Start date: Apr 12, 2020
Primary Completion: Jan 13, 2020
Completion Date: Apr 13, 2020
Study First Posted: Jan 07, 2016
Results First Posted: Aug 31, 2020
Last Updated: Dec 22, 2016

Sponsors / Collaborators

Lead Sponsor: N/A
Responsible Party: N/A

Eligibility Criteria

Sex: All
Minimum Age: 2
Maximum Age: 18

More Details

NCT Number: NCT02648412
Other IDs: Pupillo ketamine
Study URL: https://ClinicalTrials.gov/show/NCT02648412
Last updated: Jun 17, 2022