The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection
Brief Summary
Systemic inflammation caused by surgery may aggravate immunosuppression in immunocompromised cancer patients. The natural killer (NK) cell is a critical part of anti-tumor immunity. ketamine, a N-methyl-D-asparate receptor antangonist, has anti-inflammatory activity and opioid-sparing effect. This study investigate the effect of intraopertaive ketamine administration on immune function in patients undergoing laparoscopic colorectal cancer resection.
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Recruiting |
| Study results: | No Results Available |
| Age: | 20 Years to 80 Years (Adult, Older Adult) |
| Enrollment: | 100 () |
| Funded by: | Other |
Masking |
|
Clinical Trial Dates
| Start date: | Sep 01, 2017 | |
|---|---|---|
| Primary Completion: | Jul 20, 2020 | |
| Completion Date: | Jul 20, 2020 | |
| Study First Posted: | Sep 06, 2017 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Jan 16, 2019 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
Location
Eligibility Criteria
| Sex: | All |
|---|---|
| Minimum Age: | 20 |
| Maximum Age: | 80 |
This clinical trial is recruiting
Are you interested in participating in this trial or others? We'd love to help.
More Details
| NCT Number: | NCT03273231 |
|---|---|
| Other IDs: | 4-2017-0475 |
| Study URL: | https://ClinicalTrials.gov/show/NCT03273231 |
Last updated: Jun 17, 2022