Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment.
Brief Summary
the prevalence of depression in elderly is from 4 to 30% and is associated with a lower quality of life mayor medical comorbidity, and increased mortality. Although there are various treatments for depression in the elderly, the study of interventions in resistant depression is limited and there are few reports of the efficacy and safety profile of alternative interventions such as ketamine in the elderly. The final objective of the present study is to report the effects of a single infusion of ketamine on the depressive symptoms in patients undergoing ophthalmologic surgery
Condition or Disease
- Depression in Old Age
- Ketamine
Phase
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 60 Years and older (Adult, Older Adult) |
| Enrollment: | 90 () |
| Funded by: | Other |
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Clinical Trial Dates
| Start date: | Apr 15, 2018 | |
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| Primary Completion: | Jun 30, 2018 | |
| Completion Date: | Jul 30, 2018 | |
| Study First Posted: | Mar 22, 2018 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Feb 28, 2019 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
Location
The final objective of the present study is to report the effects of a single infusion of 0.5 mg / kg ketamine in infusion on depressive symptoms assessed using the scale Yesavage's abbreviated Geriatric Depression Scale.
This is a randomized double-blind follow-up study in patients over 60 years of age with ocular pathology who required ophthalmological surgery with retrobulbar block and conscious sedation with ketamine. The sample consisted of two groups: a control group and an experimental group with ketamine. The dose used for the study was 0.5mg / kg in slow infusion for two hours. In both groups the Yesavage's questionnaire was applied at three different times; Basally, at the end of the recovery and at 24 hours after the surgery.
Eligibility Criteria
| Sex: | All |
|---|---|
| Minimum Age: | 60 |
More Details
| NCT Number: | NCT03473431 |
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| Other IDs: | IMexicanoSS |
| Study URL: | https://ClinicalTrials.gov/show/NCT03473431 |
Last updated: Jun 17, 2022