Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Brief Summary
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
Condition or Disease
- Pain, Postoperative
- Ketamine Adverse Reaction
Phase
Study Design
| Study type: | Interventional |
|---|---|
| Status: | Completed |
| Study results: | No Results Available |
| Age: | 18 Years and older (Adult, Older Adult) |
| Enrollment: | 101 () |
| Funded by: | Other |
Masking |
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Clinical Trial Dates
| Start date: | Jul 01, 2017 | |
|---|---|---|
| Primary Completion: | Mar 31, 2018 | |
| Completion Date: | Nov 14, 2018 | |
| Study First Posted: | May 16, 2018 | |
| Results First Posted: | Aug 31, 2020 | |
| Last Updated: | Mar 28, 2019 |
Sponsors / Collaborators
Lead Sponsor:
N/A
Responsible Party:
N/A
Location
Postoperative pain is a world wide problem related with surgery. Multimodal analgesia may include ketamine, aimed to decrease opioid adverse effects in postoperative analgesia for major surgery, and risk of chronic postsurgical pain. Ketamine has shown efficacy as adjuvant in multimodal analgesia, however, neuropsychiatric and cardiovascular effects of ketamine at low doses in continue postoperative infusion are less known. This type of adverse effects may compromise appropriated recovery.
Objective
to determine frequency of delirium, agitation, sedation, hallucinations, bad dreams and cardiovascular changes associated with ketamine analgesic infusion treatment for postoperative pain.
Eligibility Criteria
| Sex: | All |
|---|---|
| Minimum Age: | 18 |
More Details
| NCT Number: | NCT03525912 |
|---|---|
| Other IDs: | UdeA1002 |
| Study URL: | https://ClinicalTrials.gov/show/NCT03525912 |
Last updated: Jun 17, 2022