Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers

Ketamine

Brief Summary

In recent years ketamine abuse becomes prevalent in youth in some Asian countries. Chronic ketamine abuse may lead to uropathology and cognitive impairments. No pharmacological interventions have been identified as effective for treating ketamine abuse or helpful in achieving or maintaining abstinence from ketamine. Cognitive-behavioral treatment is currently an important psychosocial intervention for addictive problems. This study aimed to test whether a brief cognitive-behavioral training program has a positive influence on stage transitions among ketamine abusers.

Intervention / Treatment

Two arms were used to examine the relative effect of the cognitive behavioral skills training (CBSR) and a time slot for education as usual (EAU). The CBST consists of six sessions. The first session is intended to establish rapport, build therapeutic cohesion through ice-breaking activities, and educate participants about the drug regulations stated in the Statute for Drug Hazard Prevention and Control. The following four sessions are devoted to interactively practicing refusal skills, communication skills, decision-making skills, and positive conflict resolution skills. The final session is to review what has been learned and reminds participants about the association of drug use with HIV/HCV.
  • Cognitive behavioral skills training (BEHAVIORAL)
    A brief cognitive behavioral skills training was applied to teach ketamine abusers about stimulus control, refusal skills, communication skills, decisional balance, and infectious diseases prevention.

Condition or Disease

  • Substance Use Disorders

Phase

  • Not Applicable

    • Study Design

    Study type: INTERVENTIONAL
    Status: Completed
    Study results: No Results Available
    Age: 18 Years to 65 Years
    Enrollment: 409 (ACTUAL)
    Funded by: Other
    Allocation: Non-Randomized
    Primary Purpose: Treatment

    Masking

    Participants signed up for a time slot for cognitive behavioral skills training (CBST) or a time slot for education as usual (EAU), without being informed which was which.

    SINGLE:
    • Participant

    Clinical Trial Dates

    Start date: Aug 19, 2014 ACTUAL
    Primary Completion: Mar 19, 2017 ACTUAL
    Completion Date: Mar 19, 2017 ACTUAL
    Study First Posted: Aug 23, 2018 ACTUAL
    Results First Posted: Aug 31, 2020
    Last Updated: Aug 21, 2018

    Sponsors / Collaborators

    Lead Sponsor: National Taiwan University
    Responsible Party: N/A

    409 ketamine abusers were recruited in this study, with 285 ketamine abusers participated in a 6-hour brief cognitive-behavioral intervention and 124 ketamine abusers attended educational lectures on ketamine abuse. A brief cognitive-behavioral intervention was applied to teach ketamine abusers about stimulus control, refusal skills, communication skills, decisional balance, and infectious diseases prevention. Stage of Change and knowledge about ketamine were assessed before and after the intervention.

    Participant Groups

    • The first session is intended to establish rapport, build therapeutic cohesion through ice-breaking activities, and educate participants about the drug regulations stated in the Statute for Drug Hazard Prevention and Control. The following four sessions are devoted to interactively practicing refusal skills, communication skills, decision-making skills, and positive conflict resolution skills. The final session is to review what has been learned and reminds participants about the association of drug use with HIV/HCV.

    • The EAU group received six hours of informational lectures about ketamine, its effects on the brain, relevant regulations and laws, and the risks and modes of transmission of infectious diseases, including HIV and hepatitis C.

    Eligibility Criteria

    Sex: All
    Minimum Age: 18
    Maximum Age: 65
    Age Groups: Adult / Older Adult
    Healthy Volunteers: Yes

    Inclusion Criteria:

    * ketamine use in 30 days
    * more than 18 years old

    Exclusion Criteria:

    * no brain damage

    Primary Outcomes

    • Stage of Change Scale: Have you thought of abstaining from Ketamine? In 30 days? In six months?

    Secondary Outcomes

    • 5 items questionnaire about consequences of using ketamine: micturition, perception distortion, depression, behavioral inhibition and memory

    More Details

    NCT Number: NCT03644719
    Other IDs: Chronic Ketamine Abusers
    Study URL: https://clinicaltrials.gov/study/NCT03644719
    Last updated: Sep 29, 2023