Post-op Ketamine Study

Brief Summary

The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption. We hypothesize that sub-anesthetic ketamine will decrease post-operative pain and narcotic consumption and may secondarily lead to shorter lengths of stay, faster rehabilitation, improved postoperative outcomes and patient satisfaction.

Intervention / Treatment

  • Drug: isotonic saline
  • Drug: Ketamine Injectable Solution

Condition or Disease

  • Osteo Arthritis Knee

Phase

Study Design

Study type: Interventional
Status: Active, not recruiting
Study results: No Results Available
Age: Child, Adult, Older Adult
Enrollment: 75 ()
Funded by: Other

Masking

Clinical Trial Dates

Start date: Mar 28, 2016
Primary Completion: Apr 27, 2018
Completion Date: Apr 27, 2019
Study First Posted: Mar 07, 2019
Results First Posted: Aug 31, 2020
Last Updated: Mar 07, 2019

Sponsors / Collaborators

Lead Sponsor: N/A
Responsible Party: N/A

Eligibility Criteria

More Details

NCT Number: NCT03865550
Other IDs: 2016Levicoff
Study URL: https://ClinicalTrials.gov/show/NCT03865550
Last updated: Jun 17, 2022