(±) 3, 4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats

DJ Mokler, SE Robinson, JA Rosecrans - European journal of …, 1987 - Elsevier

Abstract

Abstract (±) 3, 4-Methylenedioxymethamphetamine (MDMA) was administered to rats as a single 40 mg/kg injection sc or 40 mg/kg sc every second day for 4 injections. Sixteen days following the last injection rats were killed. MDMA produced significant depletions of 5-HT …

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