Correlation of tryptamine-induced convulsions in rats with brain tryptamine concentration

Abstract

Normal rat brain tryptamine concentration was 0.032±0.002 μg/g (mean±SEM). Oral administration of 0.72 mg/kg of tranylcypromine (trans 2-phenylcyclopropylamine) or 25 mg/kg of iproniazid (1-isonicotinyl-2-isopropyl hydrazine) had no apparent effect upon …