Gamma-hydroxybutyric acid as hypnotic. Clinical and pharmacokinetic evaluation of gamma-hydroxybutyric acid as hypnotic in man.

Abstract

Administered gamma-hydroxybutyric acid (GOH) to 3 groups of 4 insomniacs in 50, 75, and 100 mg/kg doses; sleep parameters (onset, awakening, and restlessness) were scored by observation and questionnaires. Results show a dose-dependent improvement in subjective …