MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy'users

Abstract

Serotonergic neurotoxicity following MDMA is well-established in laboratory animals, and neuroimaging studies have found lower serotonin transporter (SERT) binding in abstinent Ecstasy/MDMA users. Serotonin is a modulator for many different psychobiological …