Microsomal hydroxylation of tryptamine, indoleacetic acid and related compounds, to 6-hydroxy derivatives

Abstract

Liver microsomes hydroxylate tryptamine, indoleacetic acid and related indoles to the corresponding 6-hydroxy derivatives. As with other microsomal hydroxylations, TPNH and oxygen are required. Little, if any, 6-hydroxytryptamine or 6-hydroxyindoleacetic acid were …