Psilocybin as a discriminative stimulus: lack of specificity in an animal behavior model for 'hallucinogens'

Abstract

Fifteen rats were trained to discriminate between the tryptamine hallucinogen psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine; 1.0 mg/kg) and saline in a two-lever choice task. Dose-response and time-response curves were obtained. The psilocybin cue generalized to …