Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics

Abstract

Abstract Rationale 3, 4-Methylenedioxymethamphetamine (MDMA,“ecstasy”) is increasingly used by young people for its euphoric and empathic effects. MDMA presents non-linear pharmacokinetics, probably by inhibition of cytochrome P450 isoform 2D6. Users are known …