Sequential Electrophilic Trifluoromethanesulfanylation–Cyclization of Tryptamine Derivatives: Synthesis of C(3)-Trifluoromethanesulfanylated Hexahydropyrrolo[2,3-b …

Abstract

A practical and efficient synthesis of C (3)-trifluoromethanesulfanylated hexahydropyrrolo [2, 3-b] indoles 5 from tryptamine derivatives was described. The features of this synthesis included electrophilic activation of C (3) of tryptamine derivatives with “CF3S+” and cascade …