The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) in rats

KT Finnegan, JJ Skratt, I Irwin, JW Langston - Neuroscience letters, 1989 - Elsevier

Abstract

Using the systemically active, non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist dextrorphan, we explored the role of the NMDA receptor-calcium channel complex in the toxic mechanism of action of 3, 4-methylenedioxymethamphetamine …

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