The nitroethylation of indole. A new synthesis of tryptamine

Abstract

2-Nitroethanol.—2-Nitroethanol was prepared by slight modification of the method of Wieland and Sakellarios5 by adding silver nitrite (1003 g., 6.52 moles) in small portions with vigorous stirring to a solution of ethylene iodohydrin (928 g., 5.40 moles) in absolute ether …